Bundle Approach in the Prevention of Central Line Associated Blood Stream Infection (CLABSI)

Abstract

Background: Central line-associated bloodstream infection (CLABSI) remains one of the most serious healthcare-associated infections, particularly in pediatric and critical care settings. The bundle approach has emerged as an evidence-based strategy aimed at reducing CLABSI rates through the implementation of multiple preventive measures applied collectively during catheter insertion and maintenance. This approach integrates standardized protocols including strict hand hygiene, maximal barrier precautions, chlorhexidine skin antisepsis, optimal catheter site selection, daily assessment for catheter removal, aseptic maintenance practices, and standardized dressing and tubing changes. Evidence suggests that implementing these practices together significantly reduces infection rates compared with isolated interventions.