Levetiracetam: Efficacy and Safety in Children in Depth Review

Abstract

           Levetiracetam (LEV), as an antiseizure medication, is well-known for its unique mechanism of action by modulation of synaptic neurotransmitter release with significant pharmacokinetic advantages. Its efficacy includes both focal and generalized seizures as either add-on therapy or monotherapy with the highest level of tolerability especially in children. However, some studies have reported an unexplained infection like pharyngitis and rhinitis especially after long-term use.