Intralesional Candida antigen, intralesional Vitamin D, and 15% potassium hydroxide in Treatment of Molluscum contagiosum
Keywords:
Molluscum contagiosum, intralesional Candida antigen, Vitamin D, potassium hydroxide, immunotherapy, keratolytic agents.Abstract
Background: Molluscum contagiosum (MC) is a common viral cutaneous infection, usually self-limited, but often requiring treatment in cases of extensive lesions, cosmetic concerns, or immunocompromised patients. Conventional therapies include destructive methods and topical keratolytics; however, intralesional immunotherapy and novel topical agents have emerged as promising alternatives.
Conclusion: Intralesional Candida antigen and intralesional Vitamin D have shown efficacy in enhancing host cell-mediated immunity, resulting in clearance of both treated and distant lesions with low recurrence. Meanwhile, 15% potassium hydroxide (KOH), a topical keratolytic, offers a cost-effective and simple approach, though associated with local irritation. These modalities provide effective, safe, and relatively non-invasive treatment options, especially in pediatric and resistant cases.