Nano Fat Application in Treatment of Old Scars

Abstract

Nanofat is an innovative derivative of autologous fat grafting, extensively studied for its regenerative potential in both aesthetic and reconstructive plastic surgery. Unlike traditional fat grafts, nanofat is emulsified and filtered to eliminate mature adipocytes while preserving the stromal vascular fraction (SVF), which is rich in adipose-derived stem cells (ADSCs), growth factors, and cytokines. This biologically active component promotes angiogenesis, collagen remodeling, and tissue regeneration. Nanofat injections have shown promising results in facial rejuvenation, scar treatment, skin quality enhancement, and healing of chronic wounds. The simplicity of harvesting, minimal invasiveness, and autologous nature of nanofat make it a valuable tool in regenerative medicine.