An Overview on Left Atrial Appendage
Keywords:
Left atrial appendage; Atrial fibrillation; Thrombus; Stroke prevention; LAA occlusion; Cardiac anatomy.Abstract
The left atrial appendage (LAA) is a small, ear-shaped muscular structure connected to the left atrium of the heart. Although once considered a vestigial remnant, it has gained significant clinical interest due to its role in cardiovascular physiology and pathology. The LAA contributes to atrial reservoir function, secretion of atrial natriuretic peptides, and regulation of left atrial pressure. However, it is also the most common site of thrombus formation in patients with atrial fibrillation, which substantially increases the risk of ischemic stroke. Recent advances in imaging and interventional cardiology have enabled better assessment of LAA morphology and function, as well as the development of percutaneous and surgical occlusion techniques as alternatives to anticoagulation therapy.