Omega-3 Supplementation in Children with Chronic Kidney Disease

Abstract

Chronic kidney disease (CKD) affects around 10–15% of community-dwelling children and increases their risk of cardiovascular death by 2–3 times compared with the general population. The accelerated onset of cardiovascular risk may be caused by inflammation, oxidative stress, and altered metabolism, leading to vascular calcification. Dietary and supplemental omega-3 have shown vascular benefits for the general population, but effects among people with chronic kidney disease (CKD) are largely uncertain.