A Review of Dental Pulp Stem Cells in Permanent Teeth.

Abstract

Dental pulp stem cells (DPSCs) are considered as a very suitable source of cells for tissue engineering and regenerative medicine.

They can be easily available, accessible and have a close relationship with dental tissues. It has been prooved that DPSCs are capable of differentiating into various cell types, which include odontoblasts, osteoblasts and cementoblasts. This makes them potential candidates for the regeneration of damaged or lost teeth and other oral and craniofacial tissues.

The authors of this article made a research and review the current knowledge on DPSCs, including their separation, characterization, and differentiation potential. They also have discuss the potential applications of DPSCs in tissue engineering and regenerative medicine.

The authors conclude that DPSCs have a very potential for the treatment of many oral and craniofacial diseases. But still further research is needed to optimize the separation, culture, and differentiation of DPSCs and evaluation of their safety and efficacy in clinical trials.