Bioactive Compounds: Characterization And Mechanistic Research Examining the Opportunities and Difficulties in the Development of Antimicrobial and Antiviral Agents based on Plants
Keywords:
medicinal plants; bioactive compounds; antimicrobial combination effects; synergy; antagonism; metabolomics; challengesAbstract
The rising prevalence of drug-resistant diseases necessitates the rapid identification and isolation of novel bioactive components from medicinal plants via standardized contemporary analytical methods. Compounds obtained from medicinal plants may provide innovative and direct strategies against harmful microorganisms. This study examines the antimicrobial properties of plant-derived compounds, their putative modes of action, and their chemical efficacy. The emphasis is placed on the present issues and future outlook regarding the antibacterial activity of medicinal plants. There are intrinsic problems associated with the antibacterial effectiveness of medicinal plant extracts. Optimized extraction methods, tailored to specific plant species, result in enhanced and selectively extracted chemicals. antibacterial susceptibility assays for assessing the antibacterial efficacy of plant extracts may provide variable findings. The emphasis is placed on the existing obstacles, difficulties, and issues that must be addressed, as well as future possibilities about combination effects. The use of bioactive chemicals from medicinal plant extracts as suitable antimicrobials is crucial and should be enhanced using novel metabolomics methods to identify the most effective combinations. Comprehending the interactions among bioactive chemicals produced from medicinal plants will facilitate the creation of novel combination antimicrobial medicines.